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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CRY1 All Species: 31.82
Human Site: S183 Identified Species: 53.85
UniProt: Q16526 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16526 NP_004066.1 586 66395 S183 E K C T T P L S D D H D E K Y
Chimpanzee Pan troglodytes XP_509339 586 66344 S183 E K C T T P L S D D H D E K Y
Rhesus Macaque Macaca mulatta XP_001100653 586 66450 S183 E K C T T P L S D D H D E K Y
Dog Lupus familis XP_531757 606 68237 S183 E K C T T P L S D D H D E K Y
Cat Felis silvestris
Mouse Mus musculus P97784 606 67983 S183 G K C M T P L S D D H D E K Y
Rat Rattus norvegicus Q32Q86 588 66212 S183 G K C T T P L S D D H D E K Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508613 577 65001 S144 G K C M T P L S D D H D E K Y
Chicken Gallus gallus Q8QG61 621 69654 S183 Q K C T T P V S D D H D E K Y
Frog Xenopus laevis Q75WS4 523 60626 P157 F R H I S S L P D V Y T Q F R
Zebra Danio Brachydanio rerio Q4KML2 520 59903 G154 L P F S H I G G L P D V Y T Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O77059 542 62494 E148 W D P Q L V I E T N G G I P P
Honey Bee Apis mellifera NP_001077099 570 65246 K201 G S A Y T P L K E D H D D H Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785873 516 59965 Y148 S K V S H T L Y D P Q E I L A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q96524 612 69439 I184 I T A A A E A I W A C S I E E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99.4 95.3 N.A. 93.5 96.2 N.A. 85.3 87.5 25.7 25 N.A. 37.2 65.3 N.A. 59.5
Protein Similarity: 100 100 99.6 95.8 N.A. 94.7 97.7 N.A. 89.2 92.1 43.5 42.3 N.A. 53.7 78.5 N.A. 70.9
P-Site Identity: 100 100 100 100 N.A. 86.6 93.3 N.A. 86.6 86.6 13.3 0 N.A. 0 46.6 N.A. 20
P-Site Similarity: 100 100 100 100 N.A. 86.6 93.3 N.A. 86.6 100 40 6.6 N.A. 13.3 60 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. 24.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 41.9 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 15 8 8 0 8 0 0 8 0 0 0 0 8 % A
% Cys: 0 0 58 0 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 0 0 72 65 8 65 8 0 0 % D
% Glu: 29 0 0 0 0 8 0 8 8 0 0 8 58 8 8 % E
% Phe: 8 0 8 0 0 0 0 0 0 0 0 0 0 8 0 % F
% Gly: 29 0 0 0 0 0 8 8 0 0 8 8 0 0 0 % G
% His: 0 0 8 0 15 0 0 0 0 0 65 0 0 8 0 % H
% Ile: 8 0 0 8 0 8 8 8 0 0 0 0 22 0 0 % I
% Lys: 0 65 0 0 0 0 0 8 0 0 0 0 0 58 0 % K
% Leu: 8 0 0 0 8 0 72 0 8 0 0 0 0 8 0 % L
% Met: 0 0 0 15 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % N
% Pro: 0 8 8 0 0 65 0 8 0 15 0 0 0 8 8 % P
% Gln: 8 0 0 8 0 0 0 0 0 0 8 0 8 0 8 % Q
% Arg: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 8 % R
% Ser: 8 8 0 15 8 8 0 58 0 0 0 8 0 0 0 % S
% Thr: 0 8 0 43 65 8 0 0 8 0 0 8 0 8 0 % T
% Val: 0 0 8 0 0 8 8 0 0 8 0 8 0 0 0 % V
% Trp: 8 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 8 0 0 8 0 8 0 65 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _